CO129-364 - Public Offices & Others - 1909 — Page 110

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Cocainists have freqently

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of other like agents. been know to take from 30-40 grains in a day (the usual dose of cocaine hydrochloride is gr., or by hypodermic injection 2t 5 minims of a 10 per cent solution of cocaine hydrochloride) but not with impunity: the effects of chronic intoxication by cocaine are even more terrible than those of morphine. Cocainism is generally secondary to morphinism."

Hale White, Pharmacology and Therapeutics, 1901, p. 257, says:-

"A very rapid tolerance is induced and 30 or even 60 grains may be consumed daily. It is often begun by morphinists and alcoholics, but instead of replacing the other vice is often superadded to it. The cocainist becomes emaciated, the skin shrunken and pallid, the eyes sunken,

appetite and digestion fail and there may be constipation or diarrhoea. Sleeplessness is an

early and marked feature".

In the British Medical Journal, 1907, II, 555, J. Henry Chaldecott, speaking of the use of cocaine in the morphine habit, says:-

"Not only is their imediate condition rendered worse by the advent of delusions and hallucinations, but their chance of ultimate cure is very much lessened and relapses are much more common than in the cases of simple morphinian".

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